Normosol-R Injection

Multiple Electrolytes Injection Type 1

Normosol-R is a sterile, nonpyrogenic, isotonic solution for parenteral fluid and electrolyte replenishment. Normosol-R is a solution of balanced electrolytes in water for injection. The solution is administered by intravenous infusion for parenteral replacement of acute losses of extracellular fluids. Normosol-R is indicated for replacement of acute extracellular fluid volume losses in surgery, trauma, burns or shock. Normosol-R can also be used as an adjunct to restore a decrease in circulatory volume in patients with moderate blood loss.

The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as a single-dose injection. When smaller doses are required the unused portion should be discarded.

Composition:

Each 100 mL of Normosol-R contains sodium chloride, 526 mg; sodium acetate, 222 mg; sodium gluconate, 502 mg; potassium chloride, 37 mg; magnesium chloride, hexahydrate 30 mg. May contain hydrochloric acid and/or sodium hydroxide for pH adjustment. pH range 6.5 to 7.6; 295 mOsmol/liter (calc.).

Electrolytes per 1000 mL (not including pH adjustment): Sodium 140 mEq; potassium 5 mEq; magnesium 3 mEq; chloride 98 mEq; acetate 27 mEq; gluconate 23 mEq.

Dosage and Administration:

Normosol-R pH 7.4 is administered by intravenous infusion. It may also be administered subcutaneously.

The amount to be infused is based on replacement of losses of extracellular fluid volume in the individual patient.

Instruction For Use:

To Open:

Tear outer wrap at notch and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. If supplemental medication is desired, follow directions below before preparing for administration.

To Add Medication:

1. Prepare additive port.
2. Using aseptic technique and an additive delivery needle of appropriate length, puncture resealable additive port at target area, inner diaphragm and inject. Withdraw needle after injecting medication.
3. The additive port may be protected by covering with an additive cap.
4. Mix container contents thoroughly.

To Administer:

1. Attach administration set per manufacturer’s instructions.
2. Regulate rate of administration per institutional policy.

Packaging: 

• Flexible plastic container

WARNING: DO NOT USE FLEXIBLE CONTAINER IN SERIES CONNECTIONS.